WebMyo-inositol trispyrophosphate (ITPP) is an allosteric effector that reduces the oxygen-binding affinity of haemoglobin and facilitates the release of oxygen by red blood cells. We investigated herein the oxygenation effect of ITPP in six tumour models and its radiosensitizing effect in two of these models. Myo-Inositol Trispyrophosphate (ITPP) is a synthetic compound that has become popular for its potential as a performance-enhancing substance for athletes and in horse racing [1, 2]. ITPP is an inositol phosphate, which is a group of compounds that play an important role in cellular function and cell signalling … See more There is no information on the safety of ITPP. The side effects, drug interactions, and optimal dose of ITPP are all unknown. See more ITPP is banned in professional sports and is on the World Anti-Doping Agency’s prohibited list of substances [6]. See more
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