Carna plk1
WebTo study knockdown effect of small interfering RNA (siRNA) to PLK1 (Polo-like kinase 1) mRNA in colorectal cancer cell line SW480 and its mitosis and growth was changed. Ten special siRNA molecules were designed targeting different sites of PLK1 mRNA sequence and chemically synthesized. WebBTN-PLK1: Cat# 05-457-20N: Product Category: Biotinylated Kinase: Form: Wild type: Amino Acid: 1-603(end) Accession Number: NP_005021.2: Tag: N-terminal DYKDDDDK: …
Carna plk1
Did you know?
WebPolo-like kinase 1 (PLK1) plays an important role in the initiation, maintenance, and completion of mitosis. Dysfunction of PLK1 may promote cancerous transformation and … WebApr 1, 2024 · This emi2-APC/C-plk1 axis is also required to down-regulate gene expression essential for centriole amplification after differentiation is complete. These results identify an emi2-APC/C-plk1 axis that promotes and then terminates centriole assembly and basal body formation during MCC differentiation. INTRODUCTION
WebMay 13, 2024 · Through an in vitro drug screening, PLK1 or CHEK1 inhibitors (BI-2536 or prexasertib) were found to exert a superior anticancer effect against cell lines at low nanomolar concentrations and induce cell-cycle arrest. In SK-UT-1 tumor-bearing mice, BI-2536 monotherapy remarkably suppressed tumorigenicity. WebMar 13, 2024 · The well-known mitotic regulator polo-like kinase 1 (PLK1) participates in G2/M transition, DNA integrity maintenance, and the overexpression maturation of various organelles [ 9, 10, 11 ]. It has been shown that PLK1 inhibits NF-κB nuclear activation, but the related mechanism is unexplored.
WebPLK1 $219.00 SKU: 05-157 - 5 ug Carna BioSciences Available Now! Size Description Items purchased in this web store will be delivered in two to ten days. More detailed …
WebJul 15, 2024 · Polo kinase (PLK1 in mammals) is a master cell cycle regulator that is recruited to various subcellular structures, often by its polo-box domain (PBD), which binds to phosphorylated S-pS/pT motifs.
WebSep 17, 2013 · The activities of several mitotic kinases, notably cyclin-dependent kinase 1 (Cdk1), Aurora kinases and polo-like kinase 1 (Plk1), are crucial for error-free chromosome segregation. From prophase... いらすとや 本屋WebCatalog #. AM16708. Standard 5 nmol. Purification: HPLC In-Vivo Ready Standard. Size: 5 nmol 20 nmol 20 nmol 20 nmol 20 nmol 40 nmol 40 nmol 100 nmol 250 nmol 250 … いらすとや 本棚WebJan 21, 2015 · The cyclin B-dependent protein kinase Cdk1 is a master regulator of mitosis and phosphorylates numerous proteins on the minimal consensus motif Ser/Thr-Pro (S/T-P). At least in several proteins,... いらすとや 本気絵WebMar 22, 2016 · Our data highlight PLK1 as a crucial positive regulator of different modes of cell migration. This pro-migratory activity of PLK is mediated by induction of the epithelial-to-mesenchymal transition (EMT) via activation of the CRAF/MEK/ERK/Fra1/ZEB1/2 signaling cascade. Results PLK1 Weichert et al., 2004 Figure 1A Weichert et al., 2004 Figure 1A いらすとや 本を読む人WebApr 4, 2024 · PLK1 promotes proliferation and suppresses apoptosis of renal cell carcinoma cells by phosphorylating MCM3. PLK1 and NOTCH Positively Correlate in Melanoma and Their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways. いらすとや 本読むWebPLK1 is an evolutionary conserved Ser/Thr kinase that is best known for its role in cell cycle regulation and is expressed predominantly during the G2/S and M phase of the cell … pa 4th senatorial district mapWebMar 21, 2024 · PLK1 (Polo Like Kinase 1) is a Protein Coding gene. Diseases associated with PLK1 include Gonococcal Keratitis and Polyploidy . Among its related pathways are … pa 4 specifications