WebMar 15, 2004 · These analyses indicated that pulmonary arrest does not occur merely due to size restriction, and raised the question of how the tumor cell α 3 β 1 integrin contacts its … WebDec 1, 2024 · The laminin (LN) nomenclature refers to its component chains, for example, LN511 contains α5, β1, and γ1 chains. The assembly of the chains only occurs in the cytosol of mammalian cells, whereas the secreted laminin trimers exert their function extracellularly by binding to cell membrane receptors.
Laminins in Cellular Differentiation - ScienceDirect
The laminin molecules are named according to their chain composition. Thus, laminin-511 contains α5, β1, and γ1 chains. [3] Fourteen other chain combinations have been identified in vivo. The trimeric proteins intersect to form a cross-like structure that can bind to other cell membrane and extracellular … See more Laminins are a family of glycoproteins of the extracellular matrix of all animals. They are major components of the basal lamina (one of the layers of the basement membrane), the protein network foundation for most cells and organs. … See more In humans, fifteen laminin trimers have been identified. The laminins are combinations of different alpha-, beta-, and gamma-chains. • Five … See more Dysfunctional structure of one particular laminin, laminin-211, is the cause of one form of congenital muscular dystrophy. Laminin-211 is composed of an α2, β1 and γ1 chains. This laminin's distribution includes the brain and muscle fibers. In muscle, it binds to See more • Laminin domain I: all laminin alpha chains (LAMA1, LAMA2, LAMA3, LAMA4, LAMA5) • Laminin domain II: all laminin alpha chains (LAMA1, LAMA2, LAMA3, LAMA4, LAMA5) • Laminin B (domain IV): all laminin alpha chains (LAMA1, LAMA2, LAMA3, LAMA4, LAMA5), … See more Laminins form independent networks and are associated with type IV collagen networks via entactin, fibronectin, and perlecan. … See more Together with other major components of the ECM, such as collagens and fibronectin, laminins have been used to enhance mammalian cell culture, especially in the case of pluripotent … See more Laminins contain several conserved protein domains. Laminin I and Laminin II Laminins are trimeric molecules; laminin-1 is an alpha1 beta1 gamma1 trimer. It has been suggested that the domains I and II from laminin A, B1 … See more WebLaminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this … business search for kentucky
LAMA3 laminin subunit alpha 3 [ Homo sapiens (human) ]
WebSee all Laminin 5 primary antibodies Description Mouse monoclonal [P3H9-2] to Laminin 5 Host species Mouse Tested applications Suitable for: IHC-Fr more details Species reactivity Reacts with: Human Immunogen Tissue, cells or virus. This information is proprietary to Abcam and/or its suppliers. Positive control WebAs a major link between the epidermal basal cells and the papillary dermis, laminin 5 initiates hemidesmosome formation and provides stable attachment of the epidermis to … WebLaminin 332 (formerly laminin 5) is a heterotrimeric basement membrane protein composed of the alpha3, beta3 and gamma2 chains of laminin. It is expressed in skin, breast and other tissues, where it is involved in formation of hemidesmosomes and wound healing. Laminin 332 has been implicated in cancer progression. business search entity az