Thor lncrna
WeblncRNA THOR in promoting cancer cell proliferation. In addition, we found that the m6A readers YTHDF1 and YTHDF2 may play a role in balancing the gene tran-scription and decay of the lncRNA THOR.
Thor lncrna
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WebAug 1, 2024 · LncRNA THOR expression was significantly decreased in KO cells compared with that of WT control cells (**p < 0.01). d Cell proliferation analysis of WT and hTHOR −/− cells by plate colony ... WebTHOR expression was also seen to promote Renal cell carcinoma (RCC) cell growth in vitro and in vivo and can be employed as a therapeutic target . Moreover, knockdown of …
WebAnd lncRNA THOR up-regulation obviously increased the tumorigenesis of Y79 cells in vivo. In conclusion, this study makes clear that lncRNA THOR is up-regulated in retinoblastoma, … WebMar 2, 2024 · A schematic model of the role of long non-coding RNA THOR in maintaining neuroblastoma cell stemness. Mechanistically, THOR directly binds to the middle region of SOX9 3′UTR, which enhances SOX9 mRNA...
WebOct 1, 2024 · In order to investigate the biological of THOR in TSCC, the LncRNA Smart Silencer was transfected into Cal-27 and Tca8113 cells to silence THOR expression, and the transfection efficiency was verified by qRT-PCR (Fig. 2 b).Furthermore, we stably overexpressed more than 4-fold THOR in Cal-27 and Tca-8113 cells by lentivirus vector … WebSep 29, 2024 · The long noncoding RNA (lncRNA) THOR is highly conserved and expressed in various human cancer tissues, although its potential role and underlying mechanism in endometrial cancer (EC) remain unknown. This study aims to explore THOR’s biological function and molecular mechanism in EC progression. THOR expression in EC tissues and …
WebMar 21, 2024 · A novel N6-methyladenosine (m6A)-dependent fate decision for the lncRNA THOR. (PMID: 32792482) Liu H … Li Z (Cell death & disease 2024) 3 138; Long Non …
WebMar 6, 2024 · lncRNA 的失调参与了癌症的发生和进展[5-6]。 lncRNA 通过多种机制调控癌细胞中与增殖、生存、迁移、转移或多能性相关的下游基因的表达[7]。 诸多临床试验[8-9]表明，lncRNA 作为新型肿瘤相关生物标志物在早期肿瘤筛查和预测肿瘤患者临床结果方面具有重 … brass vs stainless steel telecaster saddlesWebJul 22, 2024 · THOR is a highly conserved testis-specific long noncoding RNA (lncRNA). The interaction between THOR and the development of the male reproductive system remains unclear. Herein, CRISPR/Cas9 technology was used to establish a stable THOR-deficient mouse model, and the relationship between THOR and the fertility of adult male mice was … brass vs nickel silver for watchmakingWebThe roles and mechanisms of long non-coding RNAs (lncRNA) in nasopharyngeal carcinoma (NPC) cells stemness and chemotherapeutic sensitivity are unclear. Here, Quantitative real-time PCR (qRT-PCR) was performed to detect the lncRNA THOR expression in NPC and normal adjacent tissues, adherent NPC cell … brass vs steel air hose fittingsWebApr 9, 2024 · Long non-coding RNA (LncRNA) dysregulation is associated with human osteosarcoma (OS) cell progression. Recent studies have characterized a novel but ultra … brass vs stainless steel beer faucetWebAug 1, 2024 · The findings demonstrated that the loss of the lncRNA THOR inhibits the proliferation, migration, and invasion of cancer cells in vitro and in vivo and reveal a novel long non-coding RNA regulatory mechanism, providing a new way to explore RNA epigenetic regulatory patterns in the future. Previous studies have revealed the critical roles of the … brass vs stainless steel for pressureWebAug 13, 2024 · Previous studies have revealed the critical roles of the N6-methyladenosine (m6A) modification of long non-coding RNAs (lncRNAs) in cancers, but the relationship between the oncogenic role of the lncRNA THOR (a representative of cancer/testis lncRNAs) and m6A modification remains unclear. Here, we show that the internal m6A modification … brass vs stainless steel thermowell compareWebMar 2, 2024 · LncRNA THOR was first identified as a conserved cancer RNA with oncogenic roles in 2024 . A recent study demonstrates that THOR promotes cell proliferation and metastasis in hepatocellular carcinoma . Notably, THOR facilitates liver CSC expansion by activating β-catenin signaling . brass vs stainless steel collar stays